Protein Homology Detection Through Alignment of Markov Random Fields PDF
By:Jinbo Xu,Sheng Wang,Jianzhu Ma
Published on 2015-01-22 by Springer
This work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular homology detection methods, such as Position-Specific Scoring Matrix (PSSM) and Hidden Markov Model (HMM) based methods, and then describes a novel Markov Random Fields (MRF) based method developed by the authors. MRF-based methods are much more sensitive than HMM- and PSSM-based methods for remote homolog detection and fold recognition, as MRFs can model long-range residue-residue interaction. The text also describes the installation, usage and result interpretation of programs implementing the MRF-based method.
This Book was ranked at 30 by Google Books for keyword Science Math Biological Sciences novel.
Book ID of Protein Homology Detection Through Alignment of Markov Random Fields's Books is moZfBgAAQBAJ, Book which was written byJinbo Xu,Sheng Wang,Jianzhu Mahave ETAG "ObXU3ET5k7M"
Book which was published by Springer since 2015-01-22 have ISBNs, ISBN 13 Code is 9783319149141 and ISBN 10 Code is 3319149148
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